Harvard-MIT CRS responds to the COVID-19 Pandemic

Fellows, faculty and staff in the Harvard-MIT Center for Regulatory Science (CRS) and its sister program, The Laboratory of Systems Pharmacology, are engaged in multiple new research and community projects in response to the COVID-19 pandemic. See publications here.

To address rapidly emerging shortages in medical supplies and devices, the Harvard-MIT CRS is coordinating Greater Boston Pandemic Fabrication Team (PanFab). PanFab has mobilized a team of regulatory science fellows, volunteer scientists, engineers, clinicians, and concerned citizens. The PanFab team is helping healthcare professionals, first responders and patients by using innovative approaches to alleviate shortages in medical products, coordinate product testing and promote hospital uptake of new solutions. PanFab is also studying the problems in healthcare made apparent by COVID19 from a rigorous scientific and engineering perspective and it is documenting its findings in pre-prints and peer-reviewed publications. Contact panfabteam@gmail.com for more information.

Members of the Laboratory of Systems Pharmacology (LSP) are working on rapid diagnostic tests that require a minimum of specialized equipment to perform. They are also investigating new and existing therapeutics to identify those with the potential to reduce COVID19 symptoms. Finally, the LSP is using its highly multiplexed imaging platform to investigate mechanisms of SARS-CoV-2 pathogenesis and better understand why some patients are severely affected and others are not.

All of our COVID-19 data and results are being released to the public as soon as possible using the preprint servers bioRxiv and medRxiv. For the latest information follow us

PREVIOUS CONFERENCE: Pandemic Response: Resilience and Recovery in the Era of COVID-19  |  June 23-24, 2020

Greater Boston Pandemic Fabrication Team (PanFab)
PanFab is a group of volunteer scientists, engineers, and dedicated to meeting the urgent shortage of medical supplies and equipment arising from the COVID19 pandemic.
Learn more about PanFab
COVID-19 Publications
The Center is committed to scholarship that will advance future knowledge and response for tackling future pandemics. Research on these topics can be seen at the link below.
COVID-19 Research Publications
Open Source PPE and device designs
All of our PPE designs are clinically tested under IRB protocol, and both the results and 3D printing design files are available online
See PPE Designs here